Acute pulmonary thromboembolism caused by factor V Leiden mutation in South Korea

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Acute mesenteric ischemia caused by venous thrombosis in a patient with Leiden V factor mutation.

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Factor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis

Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...

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Factor V Leiden mutation in pregnancy.

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Frequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran

Normal hemostasis requires balanced regulation of prothrombotic and antithrombotic factors. Inherited alteration of factor V and prothrombin gene, the G20210A mutation, increases the resistance of factor V to degradation and booster production of prothrombin respectively. These alterations can increase hypercoagulability leading to thrombotic consequences. We aimed to assess the frequencies of ...

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ژورنال

عنوان ژورنال: Medicine

سال: 2019

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000016318